Consult your doctor if you feel your blood pressure is too low.There may be interaction between losartan - hydrochlorothiazide and any of the following: All material copyright MediResource Inc. 1996 – 2020.
• HYZAAR 100/12.5 are white, oval, film-coated tablets, with code 745 on one side.
HYZAAR- losartan potassium and hydrochlorothiazide tablet, film coated Use in Patients with Renal Impairment: The usual regimens of therapy with HYZAAR may be followed as long as the patient's creatinine clearance is greater than 30 mL/min. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2% to 4% and 15% to 20%, respectively.Hypertension in pregnancy increases the maternal risk for pre-eclampsia, gestational diabetes, premature delivery, and delivery complications (e.g., need for cesarean section, post-partum hemorrhage). Hyzaar (Losartan Potassium-Hydrochlorothiazide) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. In long-term follow-up studies (without placebo control) the effect of losartan appeared to be maintained for up to a year. In this study, renal clearance of hydrochlorothiazide decreased by 45 and 85% in patients with mild and moderate renal impairment, respectively.Use the usual regimens of therapy with HYZAAR as long as the patient's creatinine clearance is greater than 30 mL/min. It is also not recommended for use as initial therapy in patients with intravascular volume depletion (e.g., patients treated with diuretics, see WARNINGS, Hypotension — Volume-Depleted Patients).Treatment should be initiated with COZAAR 50 mg once daily.
When pregnancy is detected, discontinue HYZAAR as soon as possible The estimated background risk of major birth defects and miscarriage for the indicated population is unknown.
Monitor calcium levels.Hydrochlorothiazide, a sulfonamide, can cause an idiosyncratic reaction, resulting in acute transient myopia and acute angle-closure glaucoma. 0006-0745-82, Because of the components Hyzaar is made up of, this drug has also been known to decrease the swelling sometimes associated with high blood pressure. HYZAAR 50/12.5 and HYZAAR 100/25 also contain D&C yellow No. DRUGS. The lower starting dose of losartan recommended for use in patients with hepatic impairment cannot be given using HYZAAR.
The maximal antihypertensive effect is attained about 3 weeks after initiation of therapy. If blood pressure remains uncontrolled after about 3 weeks of therapy, the dose may be increased to two tablets of HYZAAR 50/12.5 once daily or one tablet of HYZAAR 100/25 (losartan 100 mg/hydrochlorothiazide 25 mg) once daily.A patient whose blood pressure is inadequately controlled by 25 mg once daily of hydrochlorothiazide, or is controlled but who experiences hypokalemia with this regimen, may be switched to HYZAAR 50/12.5 (losartan 50 mg/hydrochlorothiazide 12.5 mg) once daily, reducing the dose of hydrochlorothiazide without reducing the overall expected antihypertensive response.
Patients with Hepatic Impairment: HYZAAR is not recommended for titration in patients with hepatic impairment (see WARNINGS, Impaired Hepatic Function) because the appropriate 25 mg starting dose of losartan cannot be given.The starting dose of HYZAAR for initial treatment of severe hypertension is one tablet of HYZAAR 50/12.5 once daily (see CLINICAL PHARMACOLOGY, Pharmacodynamics and Clinical Effects). There is no apparent rebound effect after abrupt withdrawal of losartan.
For patients who do not respond adequately to HYZAAR 50/12.5 after 2 to 4 weeks of therapy, the dosage may be increased to one tablet of HYZAAR 100/25 once daily.
If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately. PULMICORT TURBUHALER® (budesonide) Inhalation Powder 200 mcg.
The maximum dose is one tablet of HYZAAR 100-25 once daily.
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