Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. Oral nitrates are available in two forms: isosorbide dinitrate (ISDN) and isosorbide-5-mononitrate (ISMN). Please enable it to take advantage of the complete set of features! It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. It …
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of isosorbide mononitrate in the elderly.
Angina frequency was lower with isosorbide mononitrate than with sustained-release glyceryl trinitrate in 33 (69%) of the patients, but lower with sustained-release glyceryl trinitrate than with isosorbide mononitrate in only 3 (6%) patients (p less than 0.001). Sub-lingual glyceryl trinitrate consumption was lower with isosorbide mononitrate than with sustained-release glyceryl trinitrate in 36 (75%) patients, but lower with sustained-release glyceryl trinitrate than with isosorbide mononitrate in only 5 (10%) patients.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of isosorbide mononitrate in the elderly. He has a GTN spray for use on demand, but had not used it in the last two months. His referral letter states, ‘As he cannot take tablets for ED, could you instruct him on intra-cavernosal injection or a vacuum device.’ P value was equal to 0.0001. Our general interest e-newsletter keeps you up to date on a wide variety of health topics.In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Prescription only; 46% of people say it’s worth it; 2 dosage forms $146.27 is the lowest price near you Want to save even more money? The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.Using this medicine with any of the following medicines is not recommended. However, elderly patients are more likely to have severe low blood pressure and age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving isosorbide mononitrate. Physical exercise capacity was reported as improved in 20 (60%) patients with isosorbide mononitrate but in only 12 (25%) patients with sustained-release glyceryl trinitrate (p less than 0.02).
1984;9(2):96-106. doi: 10.1185/03007998409109566.Drugs. Curr Med Res Opin. For ISOSORBIDE MONONITRATE. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.The presence of other medical problems may affect the use of this medicine. 1987;33 Suppl 4:111-7. doi: 10.2165/00003495-198700334-00020.Cardiovasc Drugs Ther. Fifty patients entered the trial and 48 patients completed. It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. MD.
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