Your reactions could be impaired.severe stomach pain, diarrhea that is watery or bloody;sores or white patches in your mouth or throat (yeast infection or "thrush");low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, This is not a complete list of side effects and others may occur. Available for Android and iOS devices. Meropenem HEXAL Pulver zur Herstellung einer Injektions- bzw. In individuals with normal renal function, rapid renal elimination takes place. ELDEPRYL is intended for administration to Parkinsonian patients receiving levodopa/carbidopa therapy who demonstrate a deteriorating response to this treatment. The values represent the number of patients clinically cured/number of clinically evaluable patients, with the percent cure in parentheses.Sequelae were the most common reason patients were assessed as clinically not cured.Five patients were found to be bacteriologically not cured, 3 in the comparator group (1 relapse and 2 patients with cerebral abscesses) and 2 in the Meropenem group (1 relapse and 1 with continued growth of With respect to hearing loss, 263 of the 271 evaluable patients had at least one hearing test performed post-therapy.
Shake to dissolve and let stand until clear. Each 1 gram Meropenem for Injection, USP vial will deliver 1 gram of Meropenem and 90.2 mg of sodium as sodium carbonate (3.92 mEq) [The percentage of time of a dosing interval that unbound plasma concentration of Meropenem exceeds the Meropenem minimum inhibitory concentration (MIC) against the infecting organism has been shown to best correlate with efficacy in animal and in vitro models of infection.At the end of a 30-minute intravenous infusion of a single dose of Meropenem for injection in healthy volunteers, mean peak plasma concentrations of Meropenem are approximately 23 mcg/mL (range 14 to 26) for the 500 mg dose and 49 mcg/mL (range 39 to 58) for the 1 gram dose. There was no evidence of mutagenic potential found in any of these tests.In fertility studies, intravenous Meropenem was administered to male rats beginning 11 weeks before mating and throughout mating and to female rats from 2 weeks before mating through Gestation Day 7 at doses of 240, 500, and 1000 mg/kg/day. The intravenous formulation was well tolerated in animal studies.The sole metabolite of meropenem had a similar profile of toxicity in animal studies.This medicinal product must not be mixed with other medicinal products except those mentioned in section 6.6.A solution for bolus injection is prepared by dissolving the drug product meropenem in sterile water for injection to a final concentration of 50 mg/ml.Chemical and physical in-use stability for a prepared solution for bolus injection has been demonstrated upto 3 hours at controlled room temperature (15-25°C) or upto 8 hours under refrigerated conditions (2-8°C). We comply with the HONcode standard for trustworthy health information - It is (4R,5S,6S)-3-[[(3S,5S)-5-(Dimethylcarbamoyl)-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid trihydrate. At enrollment, approximately 37% of the patients had underlying diabetes, 12% had underlying peripheral vascular disease and 67% had a surgical intervention. Repeated evaluation of the patient is essential. Currently there is no additional information available to further interpret this observation.Four hundred forty-six patients (397 pediatric patients 3 months to less than 17 years of age) were enrolled in 4 separate clinical trials and randomized to treatment with Meropenem (n = 225) at a dose of 40 mg/kg every 8 hours or a comparator drug, i.e., cefotaxime (n = 187) or ceftriaxone (n = 34), at the approved dosing regimens. All reports received were consistent with events observed in the adult population.This medicinal product contains 90 mg sodium per dose, equivalent to 4.5% of the WHO recommended maximum daily intake of 2 g sodium for an adult.The maximum daily dose of this product is equivalent to ≥27% of the WHO recommended maximum daily intake for sodium. The elimination half-life for Meropenem was approximately 1.5 hours in pediatric patients of age 3 months to 2 years.The pharmacokinetics of Meropenem in patients less than 3 months of age receiving combination antibacterial drug therapy are given below. Meropenem is an antibiotic that fights bacteria. Discard unused portion.•Injection vials (500 mg and 1 gram) may be directly re-constituted with a compatible infusion fluid.•Alternatively, an injection vial may be re-constituted, then the resulting solution added to an intravenous container and further diluted with an appropriate infusion fluid [•Do not use flexible container in series connections.Compatibility of Meropenem with other drugs has not been established.
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