Fungal sensitisation in severe asthma is associated with the identification of
All subjects were moderate consumers of alcohol (< 20 g dayThe study was a randomized, open, cross‐over design comprising two phases separated by an interval of 9 days. Is Expansion of Therapeutic Drug Monitoring for Anti-Infective Agents Necessary?, Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics, Towards Safer and More Predictable Drug Treatment – Reflections from Studies of the First BCPT Prize Awardee, Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: a systematic review, Preparation and valuation of a topical solution containing eutectic mixture of itraconazole and phenol, Antifungal Therapy in Patients with Hematological Malignancies, Pulmonary Involvement in Patients with Hematological Malignancies, Bloqueo auriculoventricular avanzado en paciente en tratamiento con itraconazol, Triazole antifungal agents drug–drug interactions involving hepatic cytochrome P450, Pharmacokinetic–pharmacodynamic study of itraconazole in patients with fungal infections in intensive care units, Niveau de preuve du suivi thérapeutique pharmacologique de l’itraconazole, Antifungals: Drug Class, Mechanisms of Action, Pharmacokinetics/Pharmacodynamics, Drug‐Drug Interactions, Toxicity, and Clinical Use, Pharmacokinetic–pharmacodynamic optimization of triazole antifungal therapy, Risk of azole‐enhanced vincristine neurotoxicity in pediatric patients with hematological malignancies: Old problem – New Dilemma, Effects of Compounding on Pharmacokinetics of Itraconazole in Black-Footed Penguins (Spheniscus demersus), In vitro characterization and pharmacokinetics in mice following pulmonary delivery of itraconazole as cyclodextrin solubilized solution, Histopathologic and immunologic effects of the itraconazole treatment in a murine model of chronic pulmonary paracoccidioidomycosis, Aspergillus Spondylodiscitis in Solid Organ Transplant Recipients, Antifungal Agents and Antifungal Susceptibility Testing, Topley & Wilson's Microbiology and Microbial Infections, Synthesis and in vitro and in vivo Antifungal Activity of the Hydroxy Metabolites of Saperconazole, Clinically relevant drug interactions of current antifungal agents, Development of an itraconazole‐loaded gelatin microcapsule with enhanced oral bioavailability: physicochemical characterization and in‐vivo evaluation, Nevertheless, in patients with allergic bronchopulmonary aspergillosis, the introduction of itraconazole therapy was followed by an improvement in clinical status leading to a decrease in prednisone and methylprednisolone dosage [In our study, both corticosteroids and itraconazole were given orally. Rapidly absorbed after oral administration, with peak plasma concentrations attained within 1.5 hours. It is a slightly acidic salt (pK a = 3.7), and hence is ionisable only at very low …
Their mean ± SD age was 33.7 ± 5.2 years and body weight 62.3 ± 4.6 kg. Itraconazole is a highly lipophilic molecule. Effect on log In this study, we examined the effect of itraconazole on the pharmacokinetics and pharmacodynamics of brotizolam in healthy volunteers.
The pharmacokinetics of itraconazole have been extensively studied and are well‐documented in several reviews [18-24].
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